1) Cat. No.: TRC-G780000; 2) Chemical Name: Granisetron Hydrochloride; 3) CAS No.: 107007-99-8; 4) Mol. Formula: C18H25ClN4O; 5) Mol. Weight: 348.87; 6) Packing Size: 10mg / 100mg; 7) Appearence: White to Off-White Sold; 8) Application Notes: A specific serotonin (5HT3) receptor antagonist. Used as an antiemetic. Granisetron HCl is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve. It does not have much effect on vomiting due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptor; 9) Synonym: 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide Hydrochloride; BRL-43694A; Kytril;; 10) Solubility: Methanol, Water; 11) Storage condition: -20°C Freezer; 12) References: Kilpatrick, G.J., et al.: Nature, 330, 746 (1987), Durig, T., et al.: J. Pharm. Sci., 86, 1092